Alternative Therapies for the Treatment of Osteoporosis: Bisphosphonates

• Binds to bone to prevent resorption

• Reduces nonvertebral fractures by least 30%

• Reduces vertebral fractures by 90%

• Can be added to estrogen for combined effects

• Side effects are minimal

• Taken with a full glass of water and remain upright for 30 minutes without food or beverage

• Do not lose effect after discontinued

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